BDBM396694 6-([2,2'-bipyridin]-3- yl)imidazo[1,2-a]pyridine-3-carboxamide::US9981944, Example 39

SMILES NC(=O)c1cnc2ccc(cn12)-c1cccnc1-c1ccccn1

InChI Key InChIKey=FNBFSOZBVWJNPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396694   

TargetTGF-beta receptor type-1 [T204D](Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396694(US9981944, Example 39 | 6-([2,2'-bipyridin]-3- yl)...)
Affinity DataIC50: 6nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent

TargetTGF-beta receptor type-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM396694(US9981944, Example 39 | 6-([2,2'-bipyridin]-3- yl)...)
Affinity DataIC50: 3.72E+3nMAssay Description:Assays for the compounds reported below were conducted in 1536-well plates and 2 mL reactions are prepared from addition of HIS-TGFβR1 T204D or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent