BDBM398921 1-(3-(((S)-2,2-dimethyl-1,3- dioxolan-4-yl)methoxy)-4- methyl-1-phenyl-1H-pyrazol- 5-yl)-3-((3S,4R)-1-(2- methoxyethyl)-4-(3,4,5- trifluorophenyl)pyrrolidin-3- yl)urea::US10323022, Example 398

SMILES COCCN1C[C@@H](NC(=O)Nc2c(C)c(OC[C@H]3COC(C)(C)O3)nn2-c2ccccc2)[C@@H](C1)c1cc(F)c(F)c(F)c1

InChI Key InChIKey=LBKSNDJJDAMONY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398921   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM398921(1-(3-(((S)-2,2-dimethyl-1,3- dioxolan-4-yl)methoxy...)
Affinity DataIC50: 100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
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