BDBM399979 US10323042, Example 58

SMILES O=C(NC1CC1)c1nn2c(c1-c1cc(F)c(Cl)cc1F)OCC(F)(F)C2

InChI Key InChIKey=WSISMBBKFDPNKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 399979   

LigandChemical structure of BindingDB Monomer ID 399979BDBM399979(US10323042, Example 58)
Affinity DataIC50: 1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 399979BDBM399979(US10323042, Example 58)
Affinity DataIC50: 8.52nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 399979BDBM399979(US10323042, Example 58)
Affinity DataIC50: 16.4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 399979BDBM399979(US10323042, Example 58)
Affinity DataIC50: 156nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent