BDBM402688 5-[(3R)-3- aminopiperidin-1-yl]- N-(2- cyanophenyl)pyrazolo [1,5-a]pyrimidine-3- carboxamide trifluoroacetate::US10329294, Example 269

SMILES N[C@@H]1CCCN(C1)c1ccn2ncc(C(=O)Nc3ccccc3C#N)c2n1

InChI Key InChIKey=SEMJJVLWADSAGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 402688   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402688(US10329294, Example 269 | 5-[(3R)-3- aminopiperidi...)
Affinity DataIC50: 143nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent