BDBM4033 6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoyl)-1H-indol-2-yl]disulfanyl}-1-methyl-N-phenyl-1H-indole-3-carboxamide::dithiobis(1H-indole-3-carboxamide) deriv. 10r

SMILES COc1ccc2c(C(=O)Nc3ccccc3)c(SSc3c(C(=O)Nc4ccccc4)c4ccc(OC)cc4n3C)n(C)c2c1

InChI Key InChIKey=RDOOVEMEWGTJTD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4033   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4033(6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoy...)
Affinity DataIC50:  3.60E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4033(6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoy...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase transforming protein Src(Avian sarcoma virus)
University of Auckland

LigandPNGBDBM4033(6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoy...)
Affinity DataIC50:  3.60E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed