BDBM403442 (6R,9S)- or (6S,9R)- 4-(1-methyl-1H- pyrazol-4-yl)-6,7,8,9- tetrahydro-5H-6,9- epoxycyclo- hepta[b]pyridine-2- carboxamide::US10335399, Example 1-4A::US10806724, Example 1-4A

SMILES Cn1cc(cn1)-c1cc(nc2[C@@H]3CC[C@H](Cc12)O3)C(N)=O

InChI Key InChIKey=SOPCCMQVWBTTME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403442   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403442(US10335399, Example 1-4A | (6R,9S)- or (6S,9R)- 4-...)
Affinity DataIC50: 3.00E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2020
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM403442(US10335399, Example 1-4A | (6R,9S)- or (6S,9R)- 4-...)
Affinity DataIC50: 3.00E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent