BDBM404446 (R)-N-(1-cyanopyrrolidin- 3-yl)-5-(2-fluorophenyl)- 1H-pyrazole-3-carboxamide::US10343992, Example 98::US11066365, Example 98::US11390584, Example 98

SMILES Fc1ccccc1-c1cc(n[nH]1)C(=O)N[C@@H]1CCN(C1)C#N

InChI Key InChIKey=FYKJNMJDNJBBBE-SNVBAGLBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 404446   

TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404446((R)-N-(1-cyanopyrrolidin- 3-yl)-5-(2-fluorophenyl)...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404446((R)-N-(1-cyanopyrrolidin- 3-yl)-5-(2-fluorophenyl)...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404446((R)-N-(1-cyanopyrrolidin- 3-yl)-5-(2-fluorophenyl)...)
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent