BDBM404546 (3aR,6aR)-5-cyano-N-(4- cyano-2- fluorophenyl)hexahydro- pyrrolo[3,4-b]pyrrole- 1(2H)-carboxamide::US10343992, Example 198::US10343992, Example 199

SMILES Fc1cc(ccc1OC(=O)N1CC2CN(C[C@@H]2C1)C#N)C#N

InChI Key InChIKey=FLIRYWLIWMYKAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404546   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Missions Therapeutics

US Patent
LigandPNGBDBM404546((3aR,6aR)-5-cyano-N-(4- cyano-2- fluorophenyl)hexa...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Missions Therapeutics

US Patent
LigandPNGBDBM404546((3aR,6aR)-5-cyano-N-(4- cyano-2- fluorophenyl)hexa...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
Go to US Patent