BDBM404651 US10344000, Example 13A

SMILES C[C@]1(CCC(=CC1)c1nn(C(=O)c2c(Cl)cccc2C2CC2)c2CC(CO)CCc12)C(O)=O

InChI Key InChIKey=PKYUXKXOJJLLPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 404651   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM404651(US10344000, Example 13A)
Affinity DataIC50: 11nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2020
Entry Details
US Patent