BDBM404954 N-(pyridin-2-ylmethyl)-1-(4-{4-[2- (pyridin-3-yl)acetamido]-1H-1,2,3- triazol-1-yl}butyl)-1H-1,2,3-triazole- 4-carboxamide::US10344025, Example 298::US11370786, Example 298

SMILES O=C(Cc1cccnc1)Nc1cn(CCCCn2cc(nn2)C(=O)NCc2ccccn2)nn1

InChI Key InChIKey=LVZOWICLZZJAOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 404954   

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM404954(US10344025, Example 298 | N-(pyridin-2-ylmethyl)-1...)
Affinity DataIC50: 2.75E+3nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
University Of Texas

US Patent
LigandPNGBDBM404954(US10344025, Example 298 | N-(pyridin-2-ylmethyl)-1...)
Affinity DataIC50: 2.75E+3nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
Go to US Patent