BDBM406524 US10336739, Example 118::tert-butyl 2-{5-[6- butyl-5-(2,6- dimethoxyphenyl)- 2,4- dihydroxypyridin- 3-yl]-1,3,4- oxadiazol-2- yl}acetate

SMILES CCCCc1nc(O)c(-c2nnc(CC(=O)OC(C)(C)C)o2)c(O)c1-c1c(OC)cccc1OC

InChI Key InChIKey=FRQFCQGMLYGEIL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406524   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406524(tert-butyl 2-{5-[6- butyl-5-(2,6- dimethoxyphenyl)...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent