BDBM406660 3-{5-[(5- chloropyridin- 2-yl)methyl]- 1,3,4-oxadiazol- 2-yl}-6- (ethoxymethyl)- 5-(2-hydroxy-6- methoxyphenyl) pyridine-2,4-diol::US10336739, Example 274::US10336739, Example 275

SMILES CCOCc1nc(O)c(-c2nnc(Cc3ccc(Cl)cn3)o2)c(O)c1-c1c(O)cccc1OC

InChI Key InChIKey=OFJBKLPMIXYYMG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 406660   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406660(3-{5-[(5- chloropyridin- 2-yl)methyl]- 1,3,4-oxadi...)
Affinity DataEC50:  5.5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406660(3-{5-[(5- chloropyridin- 2-yl)methyl]- 1,3,4-oxadi...)
Affinity DataEC50:  55nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent