BDBM408104 -5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-2-iodopyrimidine::US10336775, Example 8::US11046712, No 8

SMILES CC(N1CCN(CC1)c1cnc(I)nc1)c1ccc2OCOc2c1

InChI Key InChIKey=LABKRJZPYZYTES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408104   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408104(-5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin...)
Affinity DataIC50: 125nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
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TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408104(-5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin...)
Affinity DataIC50: 125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
Go to US Patent