BDBM408238 (S)-5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-N-propyl-1,3,4-thiadiazol-2-amine::US10336775, Example 142::US11046712, No 142

SMILES CCCNc1nnc(s1)N1CCN(CC1)[C@@H](C)c1ccc2OCOc2c1

InChI Key InChIKey=AGGUNCROVWAGHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408238   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408238((S)-5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pipera...)
Affinity DataIC50: 125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM408238((S)-5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pipera...)
Affinity DataIC50: 125nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent