BDBM409295 N-((cis)-4-(4-cyanophenoxy)cyclohexyl)-6- (4-(4-cyanophenoxy)piperidine-1- carbonyl)nicotinamide::US10377742, Compound 321

SMILES O=C(N[C@H]1CC[C@H](CC1)Oc1ccc(cc1)C#N)c1ccc(nc1)C(=O)N1CCC(CC1)Oc1ccc(cc1)C#N

InChI Key InChIKey=QXYDKUCICQMFKB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409295   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM409295(N-((cis)-4-(4-cyanophenoxy)cyclohexyl)-6- (4-(4-cy...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent