BDBM409308 (R/S)-2-[6-(4-Fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyridin-1-yl]-::US10377753, Example 199

SMILES Cc1cc(ccc1F)-c1cnc2ccn(CC(=O)N3CCCC(F)C3)c2c1

InChI Key InChIKey=QVYJIOZEUNRBKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409308   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409308((R/S)-2-[6-(4-Fluoro-3-methyl-phenyl)pyrrolo[3,2-b...)
Affinity DataIC50: 200nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent