BDBM409686 N,N-Dimethyl-2-[3-methyl-6-[3-::US10377753, Example 553

SMILES CN(C)C(=O)Cn1cc(C)c2ncc(cc12)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=QTOYXPVHEBBCOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409686   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409686(N,N-Dimethyl-2-[3-methyl-6-[3- | US10377753, Examp...)
Affinity DataIC50: 79.4nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent