BDBM409744 3-Chloro-1-(3-pyridylmethyl)-6-[3-::US10377753, Example 612

SMILES FC(F)(F)c1cccc(c1)-c1cnc2c(Cl)cn(Cc3cccnc3)c2c1

InChI Key InChIKey=DQDSNKPHXQCQRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 409744   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409744(3-Chloro-1-(3-pyridylmethyl)-6-[3- | US10377753, E...)
Affinity DataIC50: 31.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent