BDBM410262 (rac)-N-(3-(6-hydroxy-4a-methyl-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide::US10377770, Example 27

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1ccc2C(O)C[C@@]3(C)COCCN3c2c1

InChI Key InChIKey=QGSMMHFVWBNAON-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410262   

LigandPNGBDBM410262((rac)-N-(3-(6-hydroxy-4a-methyl-1,2,4,4a,5,6-hexah...)
Affinity DataIC50: 0.0170nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent