BDBM411182 Methyl 2-(3-(N,N-dimethylsulfamoyl)-N-(2-methoxy-3,4′-bipyridin-3′-yl)-5-(trifluoromethyl)benzamido)acetate::US10385022, Example 178

SMILES COC(=O)CN(C(=O)c1cc(cc(c1)S(=O)(=O)N(C)C)C(F)(F)F)c1cnccc1-c1cccnc1OC

InChI Key InChIKey=ZUPUJQUUFVPSFF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411182   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411182(Methyl 2-(3-(N,N-dimethylsulfamoyl)-N-(2-methoxy-3...)
Affinity DataEC50:  49nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent