BDBM412262 US10399945, Example 1::US10669239, Compound 1::US10927079, Compound 1

SMILES CC1(C)C[C@@H](O)[C@H](NC(=O)Nc2cccnc2-c2ccccc2)c2ccccc12

InChI Key InChIKey=NAFGSIRKSYNMMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 412262   

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412262(US10399945, Example 1 | US10669239, Compound 1 | U...)
Affinity DataIC50: 0.100nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412262(US10399945, Example 1 | US10669239, Compound 1 | U...)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Mochida Pharmaceutical

US Patent
LigandPNGBDBM412262(US10399945, Example 1 | US10669239, Compound 1 | U...)
Affinity DataIC50: 50nMAssay Description:Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent