BDBM412964 6-(4-(4-cyanophenyl)-5-hydroxy-1H-pyrazol-1-yl)-N-(3-methoxypropyl)nicotinamide::US10407409, Example 148

SMILES COCCCNC(=O)c1ccc(nc1)-n1ncc(c1O)-c1ccc(cc1)C#N

InChI Key InChIKey=CTBUJEYKMRITMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412964   

TargetEgl nine homolog 1 [181-417](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM412964(US10407409, Example 148 | 6-(4-(4-cyanophenyl)-5-h...)
Affinity DataIC50: 26.9nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
7/27/2020
Entry Details
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