BDBM413135 6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)-N-(3-morpholinopropyl)nicotinamide::US10407409, Example 32

SMILES COc1cc(ccn1)-c1cnn(c1O)-c1ccc(cn1)C(=O)NCCCN1CCOCC1

InChI Key InChIKey=NOPJQBUUHCTHEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413135   

TargetEgl nine homolog 1 [181-417](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413135(6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-...)
Affinity DataIC50: 15.8nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
7/27/2020
Entry Details
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