BDBM413146 2-fluoro-4-(5-hydroxy-1-(5-(morpholine-4-carbonyl)pyridin-2-yl)-1H-pyrazol-4-yl)-5-methylbenzonitrile::US10407409, Example 398

SMILES Cc1cc(C#N)c(F)cc1-c1cnn(c1O)-c1ccc(cn1)C(=O)N1CCOCC1

InChI Key InChIKey=ZNFFKADYPCAFNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 413146   

TargetEgl nine homolog 1 [181-417](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM413146(2-fluoro-4-(5-hydroxy-1-(5-(morpholine-4-carbonyl)...)
Affinity DataIC50: 2.24nMAssay Description:The IC50 values for the PHD2 enzyme (residues 181-417) were determined by mixing increasing amounts of inhibitor with a fixed amount of enzyme (5 nM,...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
7/27/2020
Entry Details
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