BDBM414234 US10435369, Example 121

SMILES Fc1ccc(cc1)S(=O)(=O)[C@]12CC[C@H](NC(=O)Cc3ccncc3)[C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=DAXSNWYFNOXFJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 414234   

TargetNuclear receptor ROR-gamma(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM414234(US10435369, Example 121)
Affinity DataIC50: 776nMAssay Description:Inverse agonist activity of potential ligands to RORγ was measured by inhibition of luminescence in a Gal4-luciferase reporter assay in Jurkat c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
US Patent