BDBM414411 4-fluoro-N-((3R,3aS,9bS)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide and N-((3R,3aS,9bS)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)-3,6-dihydro-2H-thiopyran-4-carboxamide 1,1-dioxide::US10435369, Example 298::US10435369, Example 299
SMILES Fc1ccc(cc1)S(=O)(=O)[C@@]12CC[C@@H](NC(=O)C3(F)CCS(=O)(=O)CC3)[C@@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F
InChI Key InChIKey=AIAOIGJFDATZHZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414411
Affinity DataIC50: 5nMAssay Description:Inverse agonist activity of potential ligands to RORγ was measured by inhibition of luminescence in a Gal4-luciferase reporter assay in Jurkat c...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inverse agonist activity of potential ligands to RORγ was measured by inhibition of luminescence in a Gal4-luciferase reporter assay in Jurkat c...More data for this Ligand-Target Pair