BDBM415546 (Scheme FF) (2S,3S,4R,5R)-2-(1-methyl-1H-pyrazol-3-yl)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diol (EE-2)::US10428104, Example 77

SMILES Cc1ncnc2n(ccc12)[C@@H]1O[C@H]([C@@H](O)[C@H]1O)c1ccn(C)n1

InChI Key InChIKey=KXIVYEWRYRGNJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 415546   

TargetProtein arginine N-methyltransferase 5(Human)
Pfizer

US Patent
LigandPNGBDBM415546(US10428104, Example 77 | (Scheme FF) (2S,3S,4R,5R)...)
Affinity DataIC50: 2.44E+4nMAssay Description:Compounds were solubilized in DMSO and serially diluted, using 3-fold dilutions, into 100% DMSO at a concentration 50-fold greater than the desired a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details
US Patent