BDBM41558 US8871728, 162f

SMILES Oc1cccn(CCCCCCCn2cc(nn2)-c2ccccc2)c1=S

InChI Key InChIKey=XVMMWQTVNFSDSO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 41558   

TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Tech Research

US Patent
LigandPNGBDBM41558(US8871728, 162f)
Affinity DataIC50:  232nMT: 2°CAssay Description:Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM41558(US8871728, 162f)
Affinity DataIC50:  955nMAssay Description:Inhibition of HDAC6 (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacYGC as substrate after 60 mins by SAMDI mass spectrometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Georgia Tech Research

US Patent
LigandPNGBDBM41558(US8871728, 162f)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of HDAC8 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) using GRKacFGC as substrate after 60 mins by SAMDI mas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed