BDBM416346 3-{6-[(4- methoxycyclohexyl)carbonyl]-6,11- dihydro-5H-pyrido[2,3- b][1,5]benzodiazepin-8-yl}-4-methyl- 1,3-oxazolidin-2-one::US10442819, Example 490

SMILES COC1CCC(CC1)C(=O)N1Cc2cccnc2Nc2ccc(cc12)N1C(C)COC1=O

InChI Key InChIKey=VLWBGALFUXGQRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 416346   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM416346(US10442819, Example 490 | 3-{6-[(4- methoxycyclohe...)
Affinity DataIC50: 529nMAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series. 125 nL of each dilution or DMSO alone is disp...More data for this Ligand-Target Pair
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Date in BDB:
8/24/2020
Entry Details
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