BDBM416584 2-(4-amino-3-(6-cyclopropoxynaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-morpholinoethanone::US10307425, Example 51::US10632122, Example 51

SMILES Nc1ncnc2n(CC(=O)N3CCOCC3)nc(-c3ccc4cc(OC5CC5)ccc4c3)c12

InChI Key InChIKey=MIDMZDLZBUXDJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 416584   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

US Patent
LigandChemical structure of BindingDB Monomer ID 416584BDBM416584(US10307425, Example 51 | 2-(4-amino-3-(6-cycloprop...)
Affinity DataIC50: 15.8nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
University of Washington

US Patent
LigandChemical structure of BindingDB Monomer ID 416584BDBM416584(US10307425, Example 51 | 2-(4-amino-3-(6-cycloprop...)
Affinity DataIC50: 15.8nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent