BDBM417224 US10457654, Example 93

SMILES CN(C)[C@@H]1CC[C@H](C[C@H]1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=YYNPNJUJNNSTCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 417224   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM417224(US10457654, Example 93)
Affinity DataIC50: 64.7nMAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent