BDBM417361 US10457654, Example 220

SMILES CN(C)[C@H]1C[C@H](CC[C@@H]1Nc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=UVKDFROVVFCYAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 417361   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM417361(US10457654, Example 220)
Affinity DataIC50: 0.418nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent