BDBM418708 N-methyl-N-[3-({[2-({3-[(4- methylpiperazin-1- yl)carbonyl]phenyl}amino)-5- (trifluoromethyl)pyrimidin-4- yl]amino}methyl)pyridin-2- yl]methanesulfonamide (199), trifluoroacetic acid salt::US10450297, Example 199

SMILES CN(c1ncccc1CNc1nc(Nc2cccc(c2)C(=O)N2CCN(C)CC2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=HPJLZKCTILRJRA-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418708   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418708(N-methyl-N-[3-({[2-({3-[(4- methylpiperazin-1- yl)...)
Affinity DataIC50: 2.56nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
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Date in BDB:
8/31/2020
Entry Details
US Patent