BDBM418777 N-{3-[({2-[(4-{[(3R)-3-hydroxypiperidin-1- yl]carbonyl}phenyl)amino]-5- (trifluoromethyl)pyrimidin-4- yl}amino)methyl]pyridin-2-yl}-N- methylmethane-sulfonamide (275)::US10450297, Example 275

SMILES CN(c1ncccc1CNc1nc(Nc2ccc(cc2)C(=O)N2CCC[C@@H](O)C2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=NUZSMNOKRQXNGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418777   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418777(N-{3-[({2-[(4-{[(3R)-3-hydroxypiperidin-1- yl]carb...)
Affinity DataIC50: 2.36nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
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Date in BDB:
8/31/2020
Entry Details
US Patent