BDBM418798 N-{3-[({2-[(4-aminopyrimidin-2-yl)amino]- 5-(trifluoromethyl)pyrimidin-4- yl}amino)methyl]pyridin-2-yl}-N- methylmethane-sulfonamide (298)::US10450297, Example 298

SMILES CN(c1ncccc1CNc1nc(Nc2nccc(N)n2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=PMWAYZLBOUQMNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418798   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418798(N-{3-[({2-[(4-aminopyrimidin-2-yl)amino]- 5-(trifl...)
Affinity DataIC50: 32.8nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
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Date in BDB:
8/31/2020
Entry Details
US Patent