BDBM418898 N~2~-acetyl-N-[3-({4-[({3- [methyl(methylsulfonyl)amino]pyridin-2- yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)phenyl]glycinamide (398)::US10450297, Example 398

SMILES CN(c1cccnc1CNc1nc(Nc2cccc(NC(=O)CNC(C)=O)c2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=OCCNNBQAZVHABA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418898   

TargetFocal adhesion kinase 1 [410-689](Human)
Pfizer

US Patent
LigandPNGBDBM418898(US10450297, Example 398 | N~2~-acetyl-N-[3-({4-[({...)
Affinity DataIC50: 2.18nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
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Date in BDB:
8/31/2020
Entry Details
US Patent