BDBM419152 US10457637, Compound 17::methyl 5-[(4- ethylphenyl)isobutylsulfa- moyl]-2-(tetrahydropyran-4- ylmethylsulfanyl)benzoate

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(SCC2CCOCC2)c(c1)C(=O)OC

InChI Key InChIKey=DOZOTZXTGFHCLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419152   

TargetNuclear receptor ROR-gamma(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM419152(methyl 5-[(4- ethylphenyl)isobutylsulfa- moyl]-2-(...)
Affinity DataIC50: 1.00E+3nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
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