BDBM419824 US10464919, Example 162

SMILES O=c1[nH]c2cc(CN3C[C@@H]4C[C@H]3CN4c3ccc([N+](=O)[O-])cc3F)ccc2c2c1CCCN2

InChI Key InChIKey=BYVRMNFKQPRJNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419824   

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 419824BDBM419824(US10464919, Example 162)
Affinity DataIC50: 10.2nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent