BDBM420213 US10485800, Cmpd ID FO::US10485800, Example 169

SMILES CN1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc(F)cc4)c3c2)CC1

InChI Key InChIKey=SUPZVZQEPMOPLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 420213   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
The University of Rochester

US Patent
LigandPNGBDBM420213(US10485800, Cmpd ID FO | US10485800, Example 169)
Affinity DataIC50: 1.00E+3nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetTRAF2 and NCK-interacting protein kinase(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM420213(US10485800, Cmpd ID FO | US10485800, Example 169)
Affinity DataIC50: 19nMAssay Description:Inhibition of TNIK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed