BDBM420343 US10479788, Example 6::US11046688, Example 6

SMILES CN1CCC(CC1)NC(=O)c1ccc(Nc2cc3c(cccc3cn2)-c2cnn(C)c2)c(OC(F)(F)F)c1

InChI Key InChIKey=VTNLSEKNIBYBNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420343   

TargetDual specificity protein kinase TTK(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM420343(US10479788, Example 6 | US11046688, Example 6)
Affinity DataIC50: 293nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/25/2020
Entry Details
US Patent