BDBM421039 3-(8-Aminoimidazo[1,2-a]pyrazin-3-yl)-4-fluoro-N-(trans-4-::3-(8-Aminoimidazo[1,2-a]pyrazin-3-yl)-4-fluoro-N-(trans-4-hydroxycyclohexyl)benzenesulfonamide::US10479795, Example 42
SMILES Nc1nccn2c(cnc12)-c1cc(ccc1F)S(=O)(=O)N[C@H]1CC[C@H](O)CC1
InChI Key InChIKey=CFTDWWJBSPZBGU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 421039
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: 100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: 2.00E+3nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoSimilars
