BDBM421229 4-((3-(8-amino-6-(trifluoromethyl)imidazo[1,2-a]pyrazin-3- yl)-4-methylphenyl)sulfonyl)-1-methylpiperazin-2-one::US10479795, Example 298

SMILES CN1CCN(CC1=O)S(=O)(=O)c1ccc(C)c(c1)-c1cnc2c(N)nc(cn12)C(F)(F)F

InChI Key InChIKey=YIMXJADGBZLWDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421229   

LigandPNGBDBM421229(US10479795, Example 298 | 4-((3-(8-amino-6-(triflu...)
Affinity DataIC50: 100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent

LigandPNGBDBM421229(US10479795, Example 298 | 4-((3-(8-amino-6-(triflu...)
Affinity DataIC50: 2.00E+3nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
US Patent