BDBM421282 5-(8-Amino-6-(trifluoromethyl)imidazo[1,2- a]pyrazin-3-yl)-2-fluoro-N-(4- (hydroxymethyl)bicyclo[2.1.1]hexan-1- yl)benzenesulfonamide::US10479795, Example 398

SMILES Nc1nc(cn2c(cnc12)-c1ccc(F)c(c1)S(=O)(=O)NC12CC(CO)(C1)CC2)C(F)(F)F

InChI Key InChIKey=NKHYDJIOTHOHQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421282   

LigandPNGBDBM421282(US10479795, Example 398 | 5-(8-Amino-6-(trifluorom...)
Affinity DataIC50: 100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
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LigandPNGBDBM421282(US10479795, Example 398 | 5-(8-Amino-6-(trifluorom...)
Affinity DataIC50: 500nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/26/2020
Entry Details
Go to US Patent