BDBM42131 CEFACLOR::MLS000069617::SMR000058250::cid_51039

SMILES N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c1ccccc1

InChI Key InChIKey=QYIYFLOTGYLRGG-GPCCPHFNSA-N

Data  4 KI  10 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 42131   

TargetSolute carrier family 15 member 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataKi:  2.90E+4nMAssay Description:Binding affinity to human PepT2 in SKTP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 15 member 2(Rattus norvegicus)
Biozentrum Of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataKi:  2.90E+4nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biozentrum Of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataKi: >1.00E+7nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biozentrum Of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataKi: >1.00E+7nMAssay Description:Binding affinity against membrane transport protein PEPT1 in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50:  7.18E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Wilkes University

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human OAT3 using estrone-3-sulfate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biozentrum Of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50:  8.20E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 20 uM) in PEPT1-expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50: >5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50: >5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM42131(CEFACLOR | MLS000069617 | SMR000058250 | cid_51039)
Affinity DataIC50: >5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay