BDBM421806 US10508088, Example II-77::US10538496, Compound II-77

SMILES CC1(CCOCC1)C(=O)N1CCC2(CC1)CCc1cccc(C(=O)NO)c1O2

InChI Key InChIKey=MACFALOLYMNNOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421806   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421806(US10538496, Compound II-77 | US10508088, Example I...)
Affinity DataIC50: 1.00E+3nMAssay Description:This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2020
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM421806(US10538496, Compound II-77 | US10508088, Example I...)
Affinity DataIC50: 1.00E+3nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent