BDBM42225 MLS000571359::N-[(Z)-1-[(4-methoxyphenyl)carbamoyl]-2-(3-pyridyl)vinyl]thiophene-2-carboxamide::N-[(Z)-3-(4-methoxyanilino)-3-oxo-1-(3-pyridinyl)prop-1-en-2-yl]-2-thiophenecarboxamide::N-[(Z)-3-(4-methoxyanilino)-3-oxo-1-pyridin-3-ylprop-1-en-2-yl]thiophene-2-carboxamide::N-[(Z)-3-[(4-methoxyphenyl)amino]-3-oxidanylidene-1-pyridin-3-yl-prop-1-en-2-yl]thiophene-2-carboxamide::N-[1-{[(4-methoxyphenyl)amino]carbonyl}-2-(3-pyridinyl)vinyl]-2-thiophenecarboxamide::SMR000193444::cid_1919175

SMILES COc1ccc(NC(=O)C(\NC(=O)c2cccs2)=C\c2cccnc2)cc1

InChI Key InChIKey=QFXRNRYHUUPFCQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 42225   

TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 42225BDBM42225(cid_1919175 | N-[(Z)-3-(4-methoxyanilino)-3-oxo-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 42225BDBM42225(cid_1919175 | N-[(Z)-3-(4-methoxyanilino)-3-oxo-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
University of Pittsburgh

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 42225BDBM42225(cid_1919175 | N-[(Z)-3-(4-methoxyanilino)-3-oxo-1-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetE3 ubiquitin-protein ligase XIAP(Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 42225BDBM42225(cid_1919175 | N-[(Z)-3-(4-methoxyanilino)-3-oxo-1-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay