BDBM422292 5-[4-(6-fluoropyridin-3- yl)benzenesulfonyl]-6- hydroxy-1-[(1R)-2- methoxy-1- phenylethyl]-2-(3- methylbutyl)-1,4- dihydropyrimidin-4-one::US10508104, Example 199

SMILES COC[C@@H](c1ccccc1)n1c(O)c(c(=O)nc1CCC(C)C)S(=O)(=O)c1ccc(cc1)-c1ccc(F)nc1

InChI Key InChIKey=DZZDTJACQYUPSN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 422292   

TargetApelin receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422292(5-[4-(6-fluoropyridin-3- yl)benzenesulfonyl]-6- hy...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent