BDBM422803 US10508107, Example 9::US11312711, Example 9
SMILES Clc1cc(cnc1Cl)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1
InChI Key InChIKey=TYKADUHZARVWIN-CQSZACIVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 422803
Affinity DataKi: 480nMAssay Description:Binding to dopamine transporter (DAT) in vitro. Human embryonic kidney (HEK) 293 cells (Invitrogen, Zug, Switzerland) stably transfected with human D...More data for this Ligand-Target Pair
Affinity DataKi: 480nMAssay Description:Binding to dopamine transporter (DAT) in vitro. Human embryonic kidney (HEK) 293 cells (Invitrogen, Zug, Switzerland) stably transfected with human D...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 4.46E+3nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of the test items on hERG (human-ether-a-go-go related gene) potassium chann...More data for this Ligand-Target Pair
Affinity DataEC50: 144nMAssay Description:For the construction of expression plasmids the coding sequences of human TAAR1 were amplified from genomic DNA essentially as described by Lindemann...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 4.46E+3nMAssay Description:The whole-cell patch-clamp technique was used to investigate the effects of the test items on hERG (human-ether-a-go-go related gene) potassium chann...More data for this Ligand-Target Pair
Affinity DataEC50: 144nMAssay Description:For the construction of expression plasmids the coding sequences of human TAAR 1 were amplified from genomic DNA essentially as described by Lindeman...More data for this Ligand-Target Pair