BDBM423416 US10501467, Example 22

SMILES CC1C2=C3C(=NNC(=O)c4cccc1c43)CCC2

InChI Key InChIKey=HNRRRPQBLZKSPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423416   

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 423416BDBM423416(US10501467, Example 22)
Affinity DataIC50: 1.58E+4nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent