BDBM424694 US10508120, Compound I-1198::US10577373, Compound I-1198::US11046698, Compound I-1198
SMILES CNc1cc(Nc2cccn(C3CC(F)(F)C3)c2=O)nc2c(cnn12)C(=O)N[C@@H]1CC[C@H]1O
InChI Key InChIKey=GTSLRPITGBTOPB-UKRRQHHQSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 424694
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: <0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair